| 金黄色葡萄球菌生物膜形成机制研究进展 |
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| 引用本文： | 胡晓丰,史云,戚丽华,王勇,宋宏彬,张传福,刘雪林. 金黄色葡萄球菌生物膜形成机制研究进展[J]. 生物技术通讯, 2014, 25(5): 714-718 |
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| 作者姓名： | 胡晓丰 史云 戚丽华 王勇 宋宏彬 张传福 刘雪林 |
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| 作者单位： | 军事医学科学院疾病预防控制所,北京,100071 |
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| 基金项目： | 国家高技术研究发展计划青年科学家课题，军队"十二五"重点课题，国家传染病重大专项 |
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| 摘 要： | 金黄色葡萄球菌是医院和社区获得性感染最常见的病原菌之一,而且可形成生物膜,从而导致生物膜相关疾病的产生。患者一旦发生金黄色葡萄球菌生物膜感染,难以彻底治愈。深入研究金黄色葡萄球菌生物膜形成的分子机制和调控网络,对寻找有效的防治、治疗药物和手段具有重要意义。我们就金黄色葡萄球菌生物膜形成过程和调控机制的研究近况做一综述。
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| 关 键 词： | 金黄色葡萄球菌 生物膜 调控机制 密度信号感应系统 |
Progress on Mechanism of Staphylococcus aureus Biofilm Formation |
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| HU Xiao-Feng,SHI Yun,QI Li-Hua,WANG Yong,SONG Hong-Bin,ZHANG Chuan-Fu,LIU Xue-Lin. Progress on Mechanism of Staphylococcus aureus Biofilm Formation[J]. Letters in Biotechnology, 2014, 25(5): 714-718 |
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| Authors: | HU Xiao-Feng SHI Yun QI Li-Hua WANG Yong SONG Hong-Bin ZHANG Chuan-Fu LIU Xue-Lin |
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| Affiliation: | ( Institute for Disease Control and Prevention, Academy of Military Medical Sciences, Beijing 100071, China) |
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| Abstract: | Staphylococcus aureus is one of the most common pathogens in community acquired infection and nosocomial infection, and the biofilm formed by S.aureus can lead to biofilm associated diseases which are difficult to be completely cured. Well-understood molecular mechanisms and regulatory networks of S.aureus biofilm formation will greatly contribute to develop effective prevention and treatment medicines or approaches. In this article, we conducted a review of recent research on S.aureus biofilm formation and regulatory mechanisms. |
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| Keywords: | Staphylococcus aureus biofilm regulatory mechanisms quorum sensing system |
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