| 微流控芯片技术在细胞生物学研究中的应用进展 |
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| 引用本文： | 姚琳,白亮,吴亮其,丁永胜. 微流控芯片技术在细胞生物学研究中的应用进展[J]. 细胞生物学杂志, 2011, 0(11) |
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| 作者姓名： | 姚琳 白亮 吴亮其 丁永胜 |
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| 作者单位： | 中国科学院研究生院生命科学学院; |
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| 基金项目： | 中国科学院生物局“十二五”基础前沿专项(No.KSCX2-EW-J-29)资助项目~~ |
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| 摘 要： | 20世纪90年代以来,微流控芯片技术得到了快速发展。由于具有小型化、集成化、高通量、低消耗、分析快速等特点,微流控芯片作为一种新型的生物学研究平台,能够提供传统方法不具备的精细和可控制的细胞研究条件,在细胞生物学研究领域中得到了广泛关注。该文主要介绍其在细胞培养、分选、裂解、计数、凋亡检测、迁移、单细胞捕获、细胞间作用等方面的研究进展。
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| 关 键 词： | 微流控芯片 细胞培养 细胞分选 细胞裂解 细胞计数 细胞凋亡 细胞迁移 单细胞捕获 细胞间作用 |
Recent Applications of Microfluidic Technology in the Field of Cell Biology |
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| Yao Lin,Bai Liang,Wu Liangqi,Ding Yongsheng. Recent Applications of Microfluidic Technology in the Field of Cell Biology[J]. Chinese Journal of Cell Biology, 2011, 0(11) |
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| Authors: | Yao Lin Bai Liang Wu Liangqi Ding Yongsheng |
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| Affiliation: | Yao Lin,Bai Liang,Wu Liangqi,Ding Yongsheng~* (College of Life Sciences,Graduate University of Chinese Academy of Sciences,Beijing 100049,China) |
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| Abstract: | Since the early 1990s,microfluidics,also called lab on a chip is growing rapidly.Because of having the characteristics of miniaturization,integration,high throughput,low energy consumption and rapid analysis, microfluidics becomes attractive in cell biological research as a promising platform.Microfluidic technology enables us to investigate cell behavior with precise and localized of experimental conditions which are unreachable by using macroscopic tools.This review mainly summarizes recent applications o... |
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| Keywords: | microfluidics cell culture cell sorting cell lysis cell count cell apoptosis cell migration cell capturing cell interaction |
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