肥胖与慢性炎症的研究进展

肥胖常伴随着一系列代谢综合征的发生,肥胖引起的慢性炎症因为与各种代谢综合征的密切联系而成为目前的研究热点。慢性炎症的发生很复杂,涉及多个组织、器官和系统,并且炎症的发生会反过来影响组织的功能。目前针对慢性炎症发生机制的研究结果显示脂肪因子和免疫系统、内质网应激、细胞自噬作用以及内毒素的作用等形成的信号网络参与了慢性炎症的触发和发展。本文就慢性炎症与肥胖关联的几种可能发生机制的最新研究进展作一简要综述。

Recent Progress in Obesity and Chronic Inflammation

Obesity has always associated with an array of metabolic syndromes.Obesity-induced chronic inflammation has become one of the hottest research fields because it is closely related to the incidence of the metabolic syndromes.The occurrence of the chronic inflammation involving several tissues and systems is extremely complicated.Recent researches referring to the chronic inflammation indicated that adipokines,immune system, endoplasmic reticulum stress,autophagy,lipopolysaccharide and so on consist a signal-...