Molecular evolution of the keratin associated protein gene family in mammals,role in the evolution of mammalian hair |
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Authors: | Dong-Dong Wu David M Irwin Ya-Ping Zhang |
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Affiliation: | (1) State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, PR China;(2) Laboratory for Conservation and Utilization of Bio-resource, Yunnan University, Kunming, 650091, PR China;(3) Graduate School of the Chinese Academy of Sciences, Beijing, PR China;(4) Department of Laboratory Medicine and Pathobiology, University of Toronto, Ontario, Canada;(5) Banting and Best Diabetes Centre, University of Toronto, Ontario, Canada |
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Abstract: | Background Hair is unique to mammals. Keratin associated proteins (KRTAPs), which contain two major groups: high/ultrahigh cysteine and high glycine-tyrosine, are one of the major components of hair and play essential roles in the formation of rigid and resistant hair shafts. |
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