A novel hypothesis on the biochemical role of the Drosophila Yellow protein |
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Authors: | Drapeau Mark David |
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Affiliation: | Department of Ecology and Evolutionary Biology, University of California, Irvine 92697, USA. mdd6@nyu.edu |
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Abstract: | In Drosophila melanogaster, the protein product of the yellow gene is necessary for normal pigmentation and male sexual behavior. Although one of the best characterized loci from a genetic standpoint, the function of the Yellow protein in the development of either phenotype is unknown. Here I propose that Yellow acts as a growth factor- or hormone-like molecule in the development of pigmentation and sexual behavior, and discuss the consistency of this theory with experimental observations in flies and humans. |
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