| 蛋白4.1基因家族的研究进展 |
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| 引用本文： | 胡晓燕,周严,袁建刚,强伯勤.蛋白4.1基因家族的研究进展[J].生物化学与生物物理进展,2001,28(3):290-294. |
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| 作者姓名： | 胡晓燕 周严 袁建刚 强伯勤 |
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| 作者单位： | 中国医学科学院基础医学研究所协和医科大学基础医学院 |
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| 摘 要： | 近几年,先后发现了三种与红细胞中的4.1蛋白同源性很高的蛋白质,这四种蛋白质都具有三个功能性结构域,即膜结合结构域,血影蛋白-肌动蛋白结合结构域和羧基端结构域.而且除了已知的在细胞膜物理和生理特性维持方面的重要作用外,4.1蛋白还与有丝分裂以及神经突触的形成有关.
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| 关 键 词： | 4.1R 4.1G 4.1N 4.1B 可变剪接 |
| 收稿时间： | 2000/5/22 0:00:00 |
| 修稿时间： | 7/7/2000 12:00:00 AM |
Research Progress in Protein 4.1 Gene Family |
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| HU Xiao-Yan,ZHOU Yan,YUAN Jian-Gang and QIANG Bo-Qin.Research Progress in Protein 4.1 Gene Family[J].Progress In Biochemistry and Biophysics,2001,28(3):290-294. |
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| Authors: | HU Xiao-Yan ZHOU Yan YUAN Jian-Gang and QIANG Bo-Qin |
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| Institution: | Institute of Basic Medical Science, Chinese Academy of Medical Sciences &Peking Union Medical College, National Laboratory of Medical Molecular Biology, Beijing 100005,China;Institute of Basic Medical Science, Chinese Academy of Medical Sciences &Peking Union Medical College, National Laboratory of Medical Molecular Biology, Beijing 100005,China;Institute of Basic Medical Science, Chinese Academy of Medical Sciences &Peking Union Medical College, National Laboratory of Medical Molecular Biology, Beijing 100005,China;Institute of Basic Medical Science, Chinese Academy of Medical Sciences &Peking Union Medical College, National Laboratory of Medical Molecular Biology, Beijing 100005,China |
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| Abstract: | In recent years,three proteins that have high homology with protein 4.1 in red blood cell have been obtained.All of them involve three functional domains,membrane-binding domain,spectrin-actin binding domain and carboxyl terminal domain. Moreover,protein 4.1 is related to mitosis and the formation of the neural synapse besides that it plays an important role in maintaining the normal physical and physiological properties of the cell membrane. |
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| Keywords: | 4 1R 4 1G 4 1N 4 1B variable splicing |
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