Differential expression of the zinc finger gene Zfp105 during spermatogenesis |
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| Authors: | SA Przyborski BB Knowles MA Handel SA Gurwitch SL Ackerman |
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| Institution: | (1) The Jackson Laboratory, Bar Harbor, Maine 04609, USA, US;(2) Department of Biochemistry and Cellular and Molecular Biology, University of Tennessee, Knoxville, Tennessee 37996-0840, USA, US |
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| Abstract: | We report the isolation of Zfp105, the mouse homolog of the human ZNF35 zinc finger gene. Zfp105 and ZNF35 are highly conserved at the protein and nucleotide level, and Zfp105 maps to a region of mouse Chromosome (Chr) 9 that is homologous to the human region containing ZNF35. Zpf105 is highly expressed in the testis, especially in pachytene spermatocytes and round spermatids. The possible role of this
gene product in maintaining an ordered germ cell differentiation process is discussed.
Received: 11 February 1998 / Accepted: 1 May 1998 |
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