Androgenic control of acetate incorporation into membrane lipids in rat ventral prostate |
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Authors: | M N Recio N del Hoyo M A Pérez-Albarsanz |
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Affiliation: | Departamento de Bioquímica y Biología Molecular, Universidad de Alcalá de Henares, Madrid, Spain. |
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Abstract: | The rat ventral prostate plasma membranes incorporated acetate into total lipids, which was a time-dependent process. The acetate incorporation was mainly into phospholipids followed by cholesterol. The main phospholipids subclasses were choline and ethanolamine glycerophospholipids. Castration modified drastically both cholesterol-phospholipids and choline glycerophospholipids-ethanolamine glycerophospholipids ratios. These effects of castration were reversed after testosterone treatment, which could suggest an influence of this hormone in the modification of some lipid classes into cellular membrane. |
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