A simple capillary viscosity meter for the on-line measurement and control of the biomass concentration in high-density cultures |
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| Authors: | W J Groot R A Mijnhart R G J M van der Lans K Ch A M Luyben |
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| Institution: | (1) Department of Biochemical Engineering, Delft University of Technology, Julianalaan 67, 2628 BC Delft, The Netherlands |
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| Abstract: | A capillary viscosity meter was used for the on-line determination of the biomass concentration in a fermentation broth. At high cell densities the viscosity of the broth increases, which can be measured as the pressure drop over a capillary. Calibration aspects of this viscosity meter are presented, and the use of the device for the control of the biomass concentration in a membrane recycle fermentor is demonstrated. |
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