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感觉再训练及口服弥可保片剂对周围神经修复术后患者感觉功能的影响
引用本文:吴丽蓉 唐卫军 吕燕 李慧 马荣. 感觉再训练及口服弥可保片剂对周围神经修复术后患者感觉功能的影响[J]. 现代生物医学进展, 2014, 14(17): 3304-3307
作者姓名:吴丽蓉 唐卫军 吕燕 李慧 马荣
作者单位:[1]第三军医大学附属新桥医院神经内科,重庆400037 [2]重庆江津区中心医院肿瘤综合科,重庆402260 [3]自贡市第五人民医院神经内科,四川自贡643020 [4]第三军医大学附属新桥医院肾内科,重庆400037
摘    要:目的:探讨感觉再训练及口服弥可保片剂对周围神经修复术后患者感觉功能的影响。方法:选取2009年10月至2011年10月我院收治的腕部损伤患者128例,随机分为A、B、C、D四组,每组各32例,在神经修复术及常规治疗的基础上,D组不采取其他任何措施治疗;C组给予弥可保片剂口服治疗;B组采取感觉再训练治疗;A组采取感觉再训练联合弥可保片剂口服治疗。对比患者术后1年及2年的感觉功能恢复情况及m2-PD检测结果。结果:A、B、C组术后1年及2年的感觉功能分级情况均优于D组,差异有统计学意义(P0.05)。其中,以A组与D组相比,差异最为显著(P0.05)。并且,A组的感觉功能随着时间的延长不断改善。A、B、C组的m2-PD检测结果均优于D组,差异有统计学意义(P0.05)。其中,A组术后1年及2年的检测结果分别为(6.79±2.08)mm、(4.98±2.05)mm,相比于D组的(13.31±1.64)mm、(11.94±2.37)mm,差异最为显著(P0.05);且术后2年的的检测结果明显低于术后1年,差异有统计学意义(P0.05)。结论:将感觉再训练与弥可保口服治疗相结合用于周围神经损伤患者的神经修复术后,治疗效果更佳。能够最大限度的促进患者感觉功能的恢复。

关 键 词:感觉再训练  弥可保  周围神经修复术  感觉功能

Impacts of of Sensory Reeducation and Oral Intake of Methycobal onPatients' Sensory Function After Peripheral Nerve Regeneration
WU Li-rong,TANG Wei-jun,LV Yan,LI Hui,MA Rong. Impacts of of Sensory Reeducation and Oral Intake of Methycobal onPatients' Sensory Function After Peripheral Nerve Regeneration[J]. Progress in Modern Biomedicine, 2014, 14(17): 3304-3307
Authors:WU Li-rong  TANG Wei-jun  LV Yan  LI Hui  MA Rong
Affiliation:1 Department of Neurology, Xinqiao Hospital Affiliated Third Military Medical University, Chongqing, 400037, China; 2 Department of Comprehensive Cancer, Jiangjin District Central Hospital ofChongqing, Chongqing, 402260, China; 3 Department ofNeurology, Zigong Fifth People's Hospital, Zigong, Sichuan, 643020, China; 4 Department ofNephrology, Xinqiao Hospital Affiliated Third Military Medical University, Chongqing, 400037, China)
Abstract:Objective: To investigate the impacts of sensory reeducation and oral intake of methycobal on patients' sensory function after peripheral nerve regeneration. Methods: 128 cases of patients with wrist injury in our hospital were selected fi'om October 2009 to October 2011, and were randomly divided into four groups: A, B, C and D, each with 32 cases. Group D did not take any other therapy, Group C were given oral intake of methycobal, Group B received sensory reeducation, and Group A were treated with oral intake of methycobal combined with sensory reeducation. After 1 and 2 years, recovery of patients' sensory functions and test results of m2-PD were compared among the groups.Results: After 1 year and 2 years, sensory functions of Groups A, B, and C were superior to that of Group D with statistical significance (P〈0.05), among which the differences between Group A and Group D were the most notable (P〈0.05). What's more, sensory function of Group A improved continuously with time. Test results of m2-PD of Groups A, B and C were superior to that of Group D, also with statistical significance (P〈0.05). Among which the differences between Group A, (6.79± 2.08)mm after 1 year and(4.98± 2.05)ram after 2 years, and Group D, ( 13.31± 1.64)ram and(11.94± 2.37)mm respectively, were the most remarkable (P〈0.05). More importantly, the test results after 2 years were obviously lower than that after 1 year, which was of statistical significance (P〈0.05). Conclusion: Sensory reeducation combined with oral intake of Methycobal proves better therapeutic effect in patients with peripheral nerve injury, and may maximize the recovery of patients' sensory function.
Keywords:Sensory retraining  Methycobal  Peripheral nerve repair  Sensory function
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