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Mitochondria are required for pro‐ageing features of the senescent phenotype
Authors:Clara Correia‐Melo  Francisco DM Marques  Rhys Anderson  Graeme Hewitt  Rachael Hewitt  John Cole  Bernadette M Carroll  Satomi Miwa  Jodie Birch  Alina Merz  Michael D Rushton  Michelle Charles  Diana Jurk  Stephen WG Tait  Rafal Czapiewski  Laura Greaves  Glyn Nelson  Mohammad Bohlooly‐Y  Sergio Rodriguez‐Cuenca  Antonio Vidal‐Puig  Derek Mann  Gabriele Saretzki  Giovanni Quarato  Douglas R Green  Peter D Adams  Thomas von Zglinicki  Viktor I Korolchuk  João F Passos
Affiliation:1. Institute for Cell and Molecular Biosciences, Campus for Ageing and Vitality, Newcastle University Institute for Ageing, Newcastle University, Newcastle upon Tyne, UK;2. GABBA Program, Abel Salazar Biomedical Sciences Institute, University of Porto, Porto, Portugal;3. Institute of Cancer Sciences, CR‐UK Beatson Institute, University of Glasgow, Glasgow, UK;4. Wellcome Trust Centre for Mitochondrial Research, Newcastle University Centre for Brain Ageing and Vitality, Newcastle University, Newcastle upon Tyne, UK;5. Transgenic RAD, Discovery Sciences, AstraZeneca, M?lndal, Sweden;6. Metabolic Research Laboratories, Wellcome Trust‐MRC Institute of Metabolic Science, Addenbrooke's Hospital, University of Cambridge, Cambridge, UK;7. Faculty of Medical Sciences, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK;8. Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, USA
Abstract:
Keywords:ageing  inflammation  mitochondria     mTOR     senescence
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