Discovery of the investigational drug TAK-441, a pyrrolo[3,2-c]pyridine derivative, as a highly potent and orally active hedgehog signaling inhibitor: Modification of the core skeleton for improved solubility期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Discovery of the investigational drug TAK-441, a pyrrolo[3,2-c]pyridine derivative, as a highly potent and orally active hedgehog signaling inhibitor: Modification of the core skeleton for improved solubility

Authors:	Tomohiro Ohashi Yuya Oguro Toshio Tanaka Zenyu Shiokawa Yuta Tanaka Sachio Shibata Yoshihiko Sato Hiroko Yamakawa Harumi Hattori Yukiko Yamamoto Shigeru Kondo Maki Miyamoto Mitsuhiro Nishihara Yoshimasa Ishimura Hideaki Tojo Atsuo Baba Satoshi Sasaki

Affiliation:	Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, 26-1, Muraoka-higashi 2-chome, Fujisawa, Kanagawa 251-8555, Japan.

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