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A highly sensitive fluorescent viscosity sensor
Authors:Rahimi M Yusop  Asier Unciti-Broceta  Mark Bradley
Affiliation:School of Chemical Sciences and Food Technology, Faculty of Science and Technology, 43600 Universiti Kebangsaan Malaysia, Selangor, Malaysia.
Abstract:Variation at the 3' position of fluorescein via Suzuki-Miyaura cross-coupling with aryl and heteroaryl moieties gave a family of anthofluoresceins whose spectroscopic properties were studied. The 1-methylindole derivative gave the highest quantum yield and was observed to behave as a molecular rotor, displaying marked variations in fluorescent intensities with viscosity and offering possible application in cellular sensing and fluorescent polarisation assays.
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