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Perioperative Opioid Counseling Reduces Opioid Use Following Primary Total Joint Arthroplasty
Authors:Christopher N. Carender  Christopher A. Anthony  Edward O. Rojas  Nicolas O. Noiseux  Nicholas A. Bedard  Timothy S. Brown
Affiliation:1.Department of Orthopedics and Rehabilitation, University of Iowa Hospitals & Clinics, Iowa City, Iowa, USA;2.Penn Orthopaedics, Penn Medicine, Philadelphia, Pennsylvania, USA;3.Orthopedics & Sports Medicine in Texas Medical Center, Houston, Texas, USA
Abstract:BackgroundPreoperative counseling may reduce postoperative opioid requirements; however, there is a paucity of randomized controlled trials (RCTs) demonstrating efficacy. The purpose of this study was to perform an interventional, telehealth-based RCT evaluating the effect of peri-operative counseling on quantity and duration of opioid consumption following primary total joint arthroplasty (TJA).MethodsParticipants were randomized into three groups: 1. Control group, no perioperative counseling; 2. Intervention group, preoperative educational video; 3. Intervention group, preoperative educational video and postoperative acceptance and commitment therapy (ACT). Opioid consumption was evaluated daily for 14 days and at 6 weeks postoperatively. Best-case and worse-case intention to treat analyses were performed to account for non-responses. Bonferroni corrections were applied.Results183 participants were analyzed (63 in Group 1, 55 in Group 2, and 65 in Group 3). At 2 weeks postoperatively, there was no difference in opioid consumption between Groups 1, 2, and 3 (p>0.05 for all). At 6 weeks postoperatively, Groups 2 and 3 had consumed significantly less opioids than Group 1 (p=0.04, p<0.001) (
VariableGroupp-value
1. Control2. Video OnlyVideo + ACT
Sex (n, % female)39 (62%)32 (58%)40 (62%)0.90
Surgery (n, % THA)26 (41%)21 (38%)31 (47%)0.56
Age (mean ± SD; years)59 ± 1159 ± 1158 ± 9Overall: 0.83
1v2: 0.98
2v3: 0.65
2v3: 0.56
Prolonged Opioid Use > 60 mo. (n, %)000-
Opioid Use Within 3 mo. of Index Surgery (n, %)0 (14%)4 (7%)5 (8%)0.34
Open in a separate windowSD – standard deviation.Table 2.Quantity of Opioid Consumption at 2 Weeks Postoperatively, Best-Case Scenario
ValueGroupp-valuep-value (corrected)
1. Control2. Video OnlyVideo + ACT
Median192113901v2: 0.281v2: 0.56
IQR60-3088-30815-2481v3: 0.04*1v3: 0.15
Min0002v3: 0.472v3: 0.56
Max690623694
Open in a separate windowMedian, interquartile range (IQR), minimum (min), and maximum (max) values are reported in morphine milliequivalents (MME). * denotes statistical significance.ConclusionPerioperative opioid counseling significantly decreases the quantity and duration of opioid consumption at 6 weeks following primary TJA. Level of Evidence: I
Keywords:opioid   total hip arthroplasty   total knee arthroplasty   counseling
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