Perioperative Opioid Counseling Reduces Opioid Use Following Primary Total Joint Arthroplasty |
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Authors: | Christopher N. Carender Christopher A. Anthony Edward O. Rojas Nicolas O. Noiseux Nicholas A. Bedard Timothy S. Brown |
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Affiliation: | 1.Department of Orthopedics and Rehabilitation, University of Iowa Hospitals & Clinics, Iowa City, Iowa, USA;2.Penn Orthopaedics, Penn Medicine, Philadelphia, Pennsylvania, USA;3.Orthopedics & Sports Medicine in Texas Medical Center, Houston, Texas, USA |
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Abstract: | BackgroundPreoperative counseling may reduce postoperative opioid requirements; however, there is a paucity of randomized controlled trials (RCTs) demonstrating efficacy. The purpose of this study was to perform an interventional, telehealth-based RCT evaluating the effect of peri-operative counseling on quantity and duration of opioid consumption following primary total joint arthroplasty (TJA).MethodsParticipants were randomized into three groups: 1. Control group, no perioperative counseling; 2. Intervention group, preoperative educational video; 3. Intervention group, preoperative educational video and postoperative acceptance and commitment therapy (ACT). Opioid consumption was evaluated daily for 14 days and at 6 weeks postoperatively. Best-case and worse-case intention to treat analyses were performed to account for non-responses. Bonferroni corrections were applied.Results183 participants were analyzed (63 in Group 1, 55 in Group 2, and 65 in Group 3). At 2 weeks postoperatively, there was no difference in opioid consumption between Groups 1, 2, and 3 (p>0.05 for all). At 6 weeks postoperatively, Groups 2 and 3 had consumed significantly less opioids than Group 1 (p=0.04, p<0.001) ( | Open in a separate windowSD – standard deviation.Table 2.Quantity of Opioid Consumption at 2 Weeks Postoperatively, Best-Case ScenarioValue | Group | p-value | p-value (corrected) |
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1. Control | 2. Video Only | Video + ACT |
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Median | 192 | 113 | 90 | 1v2: 0.28 | 1v2: 0.56 | IQR | 60-308 | 8-308 | 15-248 | 1v3: 0.04* | 1v3: 0.15 | Min | 0 | 0 | 0 | 2v3: 0.47 | 2v3: 0.56 | Max | 690 | 623 | 694 | | | Open in a separate windowMedian, interquartile range (IQR), minimum (min), and maximum (max) values are reported in morphine milliequivalents (MME). * denotes statistical significance.ConclusionPerioperative opioid counseling significantly decreases the quantity and duration of opioid consumption at 6 weeks following primary TJA. Level of Evidence: I |