| VEGF与肿瘤血管生成及其在抗肿瘤药物开发中的应用 |
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| 引用本文： | 何艳,曹以诚. VEGF与肿瘤血管生成及其在抗肿瘤药物开发中的应用[J]. 生命科学, 2008, 20(2): 222-224 |
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| 作者姓名： | 何艳 曹以诚 |
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| 作者单位： | 华南理工大学生物科学与工程学院,广州,510006;华南理工大学生物科学与工程学院,广州,510006 |
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| 摘 要： | 肿瘤血管生成在肿瘤的形成和转移过程中起到很重要的作用，众多的血管生成因子和抑制因子在肿瘤血管生成中起到调控作用，而血管生成因子（VEGF）是其中很重要的一类，通过研究其在肿瘤血管形成过程的调节机制，找到了一条有效的预防和治疗肿瘤的新途径。本文就肿瘤血管生成、VEGF家族的特性、VEGF在抗肿瘤药物开发中的应用做一综述。
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| 关 键 词： | VEGF 肿瘤血管生成 抗肿瘤药物 |
| 文章编号： | 1004-0374(2008)02-0222-03 |
| 修稿时间： | 2007-08-20 |
VEGF and tumor angiogenesis and its application on anti-tumor drug exploration |
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| HE Yan,CAO Yi-cheng. VEGF and tumor angiogenesis and its application on anti-tumor drug exploration[J]. Chinese Bulletin of Life Sciences, 2008, 20(2): 222-224 |
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| Authors: | HE Yan CAO Yi-cheng |
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| Affiliation: | (Department of Bioscience and Engineering, South China University of Technology, Guangzhou 510006,China) |
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| Abstract: | Angiogenesis plays a great role on tumor growth, metastasis. A lot of an. giogenesis factors and inhibitors regulate angiogenesis. VEGF is the most important one and through the research of the regulatory mechanism of VEGF during tumor angiogenesis, a new effective way to prevent and cure cancer was found. This thesis gives a review on rumor angiogenesis, the features of VEGF family, the application of VEGF on antitumor drugs. |
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| Keywords: | VEGF： tumor angiogenesis anti-tumor drugs |
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