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Overcoming Entrenched Disagreements: the Case of Misoprostol for Post‐Partum Haemorrhage
Authors:Narcyz Ghinea  Wendy Lipworth  Miles Little  Ian Kerridge  Richard Day
Abstract:The debate about whether misoprostol should be distributed to low resource communities to prevent post‐partum haemorrhage (PPH), recognised as a major cause of maternal mortality, is deeply polarised. This is in spite of stakeholders having access to the same evidence about the risks and benefits of misoprostol. To understand the disagreement, we conducted a qualitative analysis of the values underpinning debates surrounding community distribution of misoprostol. We found that different moral priorities, epistemic values, and attitudes towards uncertainty were the main factors sustaining the debate. With this understanding, we present a model for ethical discourse that might overcome the current impasse.
Keywords:Misoprostol  post‐partum haemorrhage  Millenium Development Goals  essential medicine  pharmaceutical  off‐label  empirical ethics
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