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Advanced adenoma diagnosis with FDG PET in a visibly normal mucosa: a case report
Authors:Bhavya Rehani  Richard M Chasen  Yvonne Dowdy  Ankur Bharija  Martin Satter  Pamela Strohmeyer  Joseph Mantil
Institution:1. Addenbrookes Hospital, Cambridge University Hospitals NHS Foundation Trust, Hills Road, CB2 2QQ, Cambridge, UK
2. MRC Centre for Inflammation Research, The Queen's Medical Research Institute, 47 Little France Crescent, EH16 4TJ, Edinburgh, UK
Abstract:A 56 year old aromatherapist presented with advanced renal failure following chronic coal tar creosote vapour inhalation, and a chronic tubulo-interstitial nephritis was identified on renal biopsy. Following dialysis dependence occult inhalation continued, resulting in seizures, ataxia, cognitive impairment and marked generalised cerebral atrophy. We describe for the first time a case of creosote abuse by chronic vapour inhalation, resulting in significant morbidity. Use of the polycyclic aromatic hydrocarbon-containing wood preservative coal tar creosote is restricted by many countries due to concerns over environmental contamination and carcinogenicity. This case demonstrates additional toxicities not previously reported with coal tar creosote, and emphasizes the health risks of polycyclic aromatic hydrocarbon exposure.
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