Mapping of the Hmg1 gene and of seven related sequences in the mouse |
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| Authors: | M Gariboldi L De Gregorio S Ferrari G Manenti M A Pierotti M E Bianchi T A Dragani |
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| Institution: | (1) Division of Experimental Oncology A, Istituto Nazionale Tumori, via G. Venezian 1, 20133 Milano, Italy;(2) Dipartimento di Genetica e di Biologia dei Microorganismi, Universita'degli Studi di Milano, Via Celoria 26, 20133 Milano, Italy |
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| Abstract: | The High Mobility Group 1 protein (HMG1) is an abundant and highly conserved chromosomal protein. Mouse HMG1 is encoded by the Hmg1 gene, containing four introns, but the murine genome contains many related sequences that are mostly retrotransposed pseudogenes. By using an interspecific cross, we have mapped the functional Hmg1 gene on mouse Chromosome (Chr) 5 and seven Hmg1-related sequences on Chrs 6, 8, 17, 18, and X. |
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