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Genome-wide analysis of copy-number variation in humans with cleft lip and/or cleft palate identifies COBLL1, RIC1, and ARHGEF38 as clefting genes
Affiliation:1. Department of Pediatrics, University of Iowa, Iowa City, IA 52242, USA;2. Department of Biology, University of Iowa, Iowa City, IA 52242, USA;3. Interdisciplinary Genetics Program, University of Iowa, Iowa City, IA 52242, USA;4. Department of Pathology and Laboratory Medicine, Children’s Mercy Kansas City, Kansas City, MO 64108, USA;5. Department of Pathology, University of Missouri – Kansas City School of Medicine, Kansas City, MO 64108, USA;6. Virginia Commonwealth University, Richmond, VA 23284, USA;7. Department of Anatomy and Cell Biology, University of Iowa, Iowa City, IA 52242, USA;8. Pennsylvania State University, University Park, PA 16802, USA;9. College of Public Health, University of Iowa, Iowa City, IA 52242, USA;10. Office of Population Studies Foundation, Inc., University of San Carlos, Cebu City, Philippines;11. College of Nursing, University of Iowa, Iowa City, IA 52242, USA;12. University of North Carolina, Chapel Hill, NC 27514, USA
Abstract:
Keywords:cleft lip and palate  ARHGEF38  COBLL1  RIC1  copy number variants  craniofacial  congenital anomalies
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