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Nobiletin and related polymethoxylated flavones bind to and inhibit the nuclear export factor Exportin-1 in NK leukemia cell line KHYG-1
Institution:1. Division of Molecular Medicine, Department of Biomolecular Science, Faculty of Science, Toho University, 2-2-1 Miyama, Funabashi, Chiba, 274-8510, Japan;2. Department of Molecular Carcinogenesis, Chiba Cancer Center Research Institute, 666-2 Nitona, Chuo-ku, Chiba, 260-8717, Japan;3. Molecular Regulation of Aging, Tokyo Metropolitan Institute of Gerontology, 35-2 Sakae, Itabashi-ku, Tokyo, 173-0015, Japan;1. Department of Electrical and Electronic Engineering, Kyushu University, Fukuoka 819-0395, Japan;2. Department of Electrical Power and Machines, Cairo University, Giza 12613, Egypt;3. Tamagawa Seiki Co., Ltd., Nagano 395-8515, Japan
Abstract:
Keywords:exportin  Granzyme B  NF-κB  NK cell  Nobiletin  p53
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