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Type-3 metabotropic glutamate receptors regulate chemoresistance in glioma stem cells,and their levels are inversely related to survival in patients with malignant gliomas |
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| Authors: | C Ciceroni M Bonelli E Mastrantoni C Niccolini M Laurenza L M Larocca R Pallini A Traficante P Spinsanti L Ricci-Vitiani A Arcella R De Maria F Nicoletti G Battaglia D Melchiorri |
| Institution: | 1.IRCCS San Raffaele Pisana, Rome 00163, Italy;2.Department of Physiology and Pharmacology, University ‘Sapienza'', Rome 00185, Italy;3.Institutes of Pathology Università Cattolica del Sacro Cuore, Rome 00186, Italy;4.Institutes of Neurosurgery, Università Cattolica del Sacro Cuore, Rome 00186, Italy;5.IRCCS Neuromed, Pozzilli 86077, Italy;6.Department of Hematology, Istituto Superiore di Sanità, Rome 00161, Italy |
| Abstract: | |
| Keywords: | metabotropic glutamate receptor mGlu3 glioblastoma temozolomide cancer stem cells MGMT |