Nanowire-Based Electrode for Acute In Vivo Neural Recordings in the Brain |
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Authors: | Dmitry B Suyatin Lars Wallman Jonas Thelin Christelle N Prinz Henrik J?rntell Lars Samuelson Lars Montelius Jens Schouenborg |
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Institution: | 1. Division of Solid State Physics and The Nanometer Structure Consortium, Lund University, Lund, Sweden.; 2. Neuronano Research Center, Medical Faculty, Lund University, Lund, Sweden.; 3. Department of Measurement Technology and Industrial Electrical Engineering, Lund University, Lund, Sweden.; Faculty of Medicine University of Leipzig, Germany, |
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Abstract: | We present an electrode, based on structurally controlled nanowires, as a first step towards developing a useful nanostructured device for neurophysiological measurements in vivo. The sensing part of the electrode is made of a metal film deposited on top of an array of epitaxially grown gallium phosphide nanowires. We achieved the first functional testing of the nanowire-based electrode by performing acute in vivo recordings in the rat cerebral cortex and withstanding multiple brain implantations. Due to the controllable geometry of the nanowires, this type of electrode can be used as a model system for further analysis of the functional properties of nanostructured neuronal interfaces in vivo. |
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