| 胰岛素样生长因子2研究进展 |
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| 引用本文： | 蒋思文,彭健,熊远著. 胰岛素样生长因子2研究进展[J]. 遗传, 2004, 26(2): 271-273 |
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| 作者姓名： | 蒋思文 彭健 熊远著 |
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| 作者单位： | 胰岛素样生长因子2；印迹；数量性状基因座 Key words: insulin-like growth factor 2; imprinting; quantitative trait locus |
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| 基金项目： | 国家重点基础研究发展计划(973计划)，国家高技术研究发展计划(863计划) |
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| 摘 要： | 胰岛素样生长因子2在胎儿生长发育、肿瘤细胞增殖、肌肉生长等方面具有重要的调控作用。本文综述了胰岛素样生长因子2基因结构、基因组印迹和作为影响肌肉重量数量性状基因座的研究进展。Abstract: Insulin-like growth factors play an important role in fetal growth and development, tumour cell proliferation and muscle growth. This review is focused on the insulin-like growth factor 2 gene structures, and their imprintings in mammalian genomes. In addition, we also discussed that IGF2 is the major paternally expressed candidate gene affecting muscle mass.
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| 关 键 词： | 华中农业大学动物科学技术学院 武汉 China Huanzhong Agricultural University. Wuhan 430070 430070 College of Animal Science and Technology |
| 文章编号： | 0253-9772(2004)02-0271-03 |
| 修稿时间： | 2003-02-17 |
Advance on insulin-like growth factor 2 |
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| JIANG Si-Wen,PENG Jian,XIONG Yuan-Zhu. Advance on insulin-like growth factor 2[J]. Hereditas, 2004, 26(2): 271-273 |
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| Authors: | JIANG Si-Wen PENG Jian XIONG Yuan-Zhu |
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| Affiliation: | College of Animal Science and Technology, Huanzhong Agricultural University, Wuhan 430 070, China. jiangsiwen@hotmail.com |
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| Abstract: | Insulin-like growth factors play an important role in fetal growth and development, tumour cell proliferation and muscle growth. This review is focused on the insulin-like growth factor 2 gene structures, and their imprintings in mammalian genomes. In addition, we also discussed that IGF2 is the major paternally expressed candidate gene affecting muscle mass. |
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| Keywords: | insulin-like growth factor 2 imprinting quantitative trait locus |
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