Analysis for linkage between F13A and three chromosome 6 marker loci: evidence for 6pter: F13A:HLA:GL01:cen gene order |
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| Authors: | P Wong L Komarnicki ML Schroeder M Lewis H Kaita S Philipps L Stranc P J McAlpine |
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| Institution: | (1) Deparment of Human Genetics, University of Manitoba, 250-770 Bannatyne Avenue, R3E OW3 Winnipeg, Manitoba, Canada;(2) Children's Hospital of Winnipeg, 840 Sherbrook Street, R3A 1S1 Winnipeg, Manitoba, Canada;(3) Rh Laboratory, Department of Paediatrics, University of Manibota, 735 Notre Dame Avenue, R3E 0L8 Winnipeg, Manitoba, Canada |
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| Abstract: | Summary The results of the present study provide independent support for F13A:HLA linkage and refine the F13A: HLA and F13A: GLO1 linkage relationships. Analysis of the corresponding recombination fractions for the total paternal F13A:HLA and F13A:GLO1 peak lod scores( ) indicates a locus order of 6pter: F13A:HLA:GLO1:cen. Lod scores between F13A and PLG, a locus recently assigned to chromosome 6, exclude close linkage between these loci. |
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