Continuous culture of Streptococcus cremoris on lactose using various medium conditions

Summary Growth of a lactic streptococcus was studied in continuous cultures, under various conditions of medium richness, without carbon source limitation, and with a large range of dilution rates. Increasing the concentrations of growth factors and protein nitrogen sources resulted in increased volumetric productivities of biomass and lactic acid with maximum values in the 0.3–0.4 h^–1 dilution rate range. Growth was shown to be dependent on both the inhibitory effect of lactic acid and the availability of certain nutrients, as has previously been shown for batch cultures.Offprint requests to: A. Pareilleux