| 细菌的群体性行为与耐药 |
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| 引用本文： | 王辉,杨崇广,牛辰.细菌的群体性行为与耐药[J].微生物与感染,2011,6(2):122-126. |
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| 作者姓名： | 王辉 杨崇广 牛辰 |
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| 作者单位： | 复旦大学上海医学院教育部/卫生部医学分子病毒学重点实验室,上海,200032 |
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| 基金项目： | 上海市卫生局青年科研项目 |
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| 摘 要： | 随着抗生素的广泛使用,细菌耐药已经成为一个严重的问题。细菌耐药是一个复杂的过程,涉及宿主、细菌与环境等几个既相互独立又相互作用的因素。很久以来,人们认为细菌以个体为单位进行各种活动,直到发现细菌相互之间也存在联系,才意识到细菌群体对其个体生存的重要性。目前将细菌作为一个群体来研究其耐药行为与机制的研究越来越多,特别是细菌生物膜与细菌程序性死亡两方面受到极大重视。本文综述了细菌生物膜、细菌程序性死亡与耐药相关机制的研究进展。
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| 关 键 词： | 细菌 耐药 生物膜 程序性死亡 |
Bacterial group behavior and drug resistance |
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| WANG Hui,YANG Chong-Guang,NIU Chen.Bacterial group behavior and drug resistance[J].Journal of Microbes and Infection,2011,6(2):122-126. |
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| Authors: | WANG Hui YANG Chong-Guang NIU Chen |
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| Institution: | WANG Hui,YANG Chong-Guang,NIU Chen Key Laboratory of Medical Molecular Virology,Ministry of Education and Health,Shanghai Medical College,Fudan University,Shanghai 200032,China |
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| Abstract: | With the increasing usage of antibiotics,bacterial drug resistance has become a serious problem.Bacterial drug resistance is a complex process,involving the host,bacteria and environment,which are independent and interactive factors.For a long time,scientists considered that bacteria behave as individual.Till recently,people found that bacteria communicate with each other.We begin to realize the importance of bacterial group behavior in survival.An increasing number of studies have tended to take bacteria a... |
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| Keywords: | Bacteria Drug resistance Biofilm Programmed cell death |
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