Abstract: | As revealed, antihepatocitotoxic serum caused a sharp suppression of antibody genesis in rats at the early period (the 3rd day) after its 5 administrations; this was indicated by a marked reduction of the antibody-forming cell count in the spleen and reduction of the circulating antibody titres (hemolysins and hemagglutinins). Along with this, antibody formation was stimulated in the liver in the course of the whole month of study. By the end of the month suppression of antibody formation was replaced by its stimulation. |