2-Methylsorbic acid,an antifungal metabolite of Penicillium vermiculatum |
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| Authors: | Bohumil Proksa Jana Adamcová Ján Fuska |
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| Affiliation: | (1) Institute of Chemistry, Slovak Academy of Sciences, 84238 Bratislava, Czechoslovakia;(2) Department of Biochemical Technology, Faculty of Chemistry, Slovak Technical University, 81237 Bratislava, Czechoslovakia |
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| Abstract: | Summary 2-Methylsorbic acid (MA), (2Z,4E)-2-methyl-2,4-hexadienoic acid, is a new metabolite of Penicillium vermiculatum. Antifungal activity of this acid was higher than that of sorbic acid or the bromoderivatives bromomethylsorbic acid and bromosorbic acid. MA suppressed the growth of Talaromyces flavus and germination of its conidia. In P. vermiculatum this acid lowered production of vermiculin and inhibited proteosynthesis in Saccharomyces cerevisiae.Correspondence to: B. Proksa |
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