Sedative actions of Ternstroemia sylvatica in the male rat. |
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Authors: | M Molina C M Contreras P Tellez-Alcantara F Rodriguez |
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Institution: | Laboratorio de Conducta, Universidad Veracruzana, México. mimoli@bugs.invest.uv.mx |
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Abstract: | Ternstroemia sylvatica is a plant reputed popularly to possess a anxiolytic properties but has not yet been systematically tested for such activity. The behavioral actions of T. sylvatica were examined using the open field test, the elevated plus-maze test, and the forced swim test in male rats. T. sylvatica (7.1 mg/kg and 14.2 mg/kg, i.p.) reduced ambulatory behavior in the open field test and cancelled the anti-immobility actions produced by desipramine (32 mg/kg, i.p.) in the forced swim test, as did diazepam. In the elevated plus-maze test, T. sylvatica (7.1 mg/kg, i.p.) failed to show anxiolytic actions. It is concluded that Ternstroemia sylvatica produces sedative effects rather than the attributed anxiolytic actions. |
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