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The Mini Mental State Examination at the Time of Alzheimer's Disease and Related Disorders Diagnosis,According to Age,Education, Gender and Place of Residence: A Cross-Sectional Study among the French National Alzheimer Database
Authors:Christian Pradier  Charlotte Sakarovitch  Franck Le Duff  Richard Layese  Asya Metelkina  Sabine Anthony  Karim Tifratene  Philippe Robert
Institution:1. Department of Public Health, Nice University Hospital and University of Nice Sophia Antipolis, Nice, France.; 2. Department of Clinical Research, Nice University Hospital Nice, Nice, France.; 3. CoBTeK Research Unit, University of Nice Sophia Antipolis, Nice, France.; 4. Memory Center – CMRR, Nice University Hospital, Nice, France.; University Of São Paulo, Brazil,
Abstract:

The aim of this study

was firstly to describe the MMSE (Mini-Mental State Examination) score upon initial diagnosis of Alzheimer''s disease and related disorders among the French population, according to age. Secondly, education, gender and place of residence were studied as factors potentially associated with delayed Alzheimer''s disease diagnosis.

Design

we conducted a cross sectional analysis of the French National Alzheimer database (BNA). Data from 2008 to 2012 were extracted. Patients were selected at the moment of their first diagnosis of AD (n = 39,451).

Results

The MMSE score at initial diagnosis dropped significantly with increasing age. The test score increased with the degree of educational background regardless of age. Gender and place of residence were significantly related to the MMSE score, women and persons living in medical institutions having lower MMSE scores under the age of 90 years and at all educational levels.

Conclusions

Health care professionals should be aware of these risk factors in order to maximize chances of earliest possible diagnosis of Alzheimer''s disease and related disorders.
Keywords:
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