GMEnzy: A Genetically Modified Enzybiotic Database |
| |
| Authors: | Hongyu Wu Jinjiang Huang Hairong Lu Guodong Li Qingshan Huang |
| |
| Affiliation: | 1. State Key Laboratory of Genetic Engineering, Institute of Genetics, School of Life Sciences, Fudan University, Shanghai, China.; 2. Shanghai Engineering Research Center Of Industrial Microorganisms, Shanghai, China.; 3. Shanghai High-Tech United Bio-Technological R&D Co., Ltd., Shanghai, China.; University of Lausanne, Switzerland, |
| |
| Abstract: | GMEs are genetically modified enzybiotics created through molecular engineering approaches to deal with the increasing problem of antibiotic resistance prevalence. We present a fully manually curated database, GMEnzy, which focuses on GMEs and their design strategies, production and purification methods, and biological activity data. GMEnzy collects and integrates all available GMEs and their related information into one web based database. Currently GMEnzy holds 186 GMEs from published literature. The GMEnzy interface is easy to use, and allows users to rapidly retrieve data according to desired search criteria. GMEnzy’s construction will increase the efficiency and convenience of improving these bioactive proteins for specific requirements, and will expand the arsenal available for researches to control drug-resistant pathogens. This database will prove valuable for researchers interested in genetically modified enzybiotics studies. GMEnzy is freely available on the Web at http://biotechlab.fudan.edu.cn/database/gmenzy/. |
| |
| Keywords: | |
|
|
