Cancer cell metabolism: Warburg and beyond |
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| Authors: | Hsu Peggy P Sabatini David M |
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| Affiliation: | Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology Department of Biology, Cambridge, MA 02142, USA. |
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| Abstract: | Described decades ago, the Warburg effect of aerobic glycolysis is a key metabolic hallmark of cancer, yet its significance remains unclear. In this Essay, we re-examine the Warburg effect and establish a framework for understanding its contribution to the altered metabolism of cancer cells. |
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