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Unresolved ER Stress Inflames the Intestine
Authors:Ma Averil
Affiliation:Department of Medicine, University of California at San Francisco, San Francisco, CA 94143-0451, USA.
Abstract:Intestinal epithelial cells interact with both microbes in the gut lumen and host immune cells. In this issue, Kaser et al. (2008) link a key mediator of endoplasmic reticulum stress, the protein XBP1, with survival of intestinal secretory epithelial cells and inflammatory bowel disease.
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