Erythrocyte G-6-PD and 6-PGD genetic polymorphisms in South African Negroes,with a note on G-6-PD and the malaria hypothesis |
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| Authors: | H W Hitzeroth K Bender |
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| Institution: | (1) Africa Institute of South Africa, P.O. Box 630, Pretoria, Republic of South Africa;(2) Institut für Humangenetik und Anthropologie der Universität, Albertstrasse 11, D-7800 Freiburg, Federal Republic of Germany |
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| Abstract: | Summary Sample of 981 and 998 South African Negroes belonging to seven different ethnic groups were screned for G-6-PD and 6-PGD phenotypes, respectively. The results are discussed in terms of the interethnic variability and the possible adaptive values of these genetic polymorphisms. Particular attention is paid to the geographic co-distribution and interrelationship of G-6-PD deficiency and the occurrence of malaria in South Africa. |
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