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Molecularly imprinted polymer films for reflectometric interference spectroscopic sensors |
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| Authors: | Belmont Anne-Sophie Jaeger Stefanie Knopp Dietmar Niessner Reinhard Gauglitz Guenter Haupt Karsten |
| Affiliation: | aLund University, Pure and Applied Biochemistry, Sweden bUniversity of Tuebingen, Institute of Physical and Theoretical Chemistry, Germany cTechnical University of Munich, Institute for Water Chemistry and Chemical Balneology, Germany dCompiègne University of Technology, UMR CNRS 6022, BP 20529, 60205 Compiègne Cedex, France |
| Abstract: | Reflectometric interference spectroscopic measurements were performed on molecularly imprinted polymer (MIP) films with the herbicide atrazine as the template molecule. A conventional imprinting protocol was used relying on non-covalent interactions between the functional monomers and the template. The MIPs were deposited on glass transducers by two different methods: spin-coating followed by in situ polymerization of thin films of monomers containing a sacrificial polymeric porogen, and autoassembly of MIP nanoparticles with the aid of an associative linear polymer. Reproducible results were obtained upon measurements of atrazine solutions in toluene with both films. Atrazine concentrations as low as 1.7 ppm could be detected with the autoassembled particle film. No or very little analyte adsorption was observed onto non-imprinted control films made by spin-coating and by particle assembly, respectively. We believe that these MIP layers in combination with the general reflectrometric transduction scheme could be a versatile sensing tool for the detection of environmentally important and other analytes. |
| Keywords: | Synthetic receptor Chemical sensor Molecularly imprinted polymer Reflectometric interference spectroscopy Thin film |
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