SLE and malaria: another look at an old idea

An alternative view of the relationship between autoimmune disease and malaria is provided in the following article by Geoff Butcher and Ian Clark. Here they reassess the evidence that favours an earlier suggestion that where parasitic infections are common, autoimmune disease is rare. They suggest that malaria may exert a protective effect against the autoimmune nephritis in systemic lupus erythematosus (SLE).