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Design and syntheses of melanocortin subtype-4 receptor agonists. Part 2: discovery of the dihydropyridazinone motif |
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| Authors: | Ujjainwalla Feroze Warner Daniel Snedden Christine Grisson Ricky D Walsh Thomas F Wyvratt Matthew J Kalyani Rubana N Macneil Tanya Tang Rui Weinberg David H Van der Ploeg Lex Goulet Mark T |
| Institution: | Department of Medicinal Chemistry, Merck Research Laboratories, Rahway, NJ 07065-0900, USA. f_ujjainwalla@merck.com |
| Abstract: | Optimization of the biological activity of a new class of non-peptidyl, pyridazinone derived human melanocortin subtype-4 receptor agonists is disclosed. |
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