CHOLESTEROL, CHOLESTEROL ESTERS AND CHOLESTEROL ESTERASE IN THE SCIATIC NERVE DURING DEVELOPMENT OF THE CHICK |
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| Authors: | Catherine Mezei R W Newburgh T Hattori |
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| Institution: | Department of Biochemistry and Biophysics, Oregon State University, Corvallis, Oregon 97331 |
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| Abstract: | Abstract— Changes in the contents of cholesterol and cholesterol ester and in the activity of cholesterol esterase (EC 3.1.1.13) in the sciatic nerve of the chick during development were measured. The ratio of cholesterol ester/cholesterol was an inverse function of the activity of the esterase (i.e. when the ratio was high, the activity of the enzyme was low, and vice versa). The synthesis of cholesterol esterase was inhibited after addition of actinomycin D both in ovo and in vitro. |
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