首页 | 本学科首页   官方微博 | 高级检索  
   检索      


Self-similar mitochondrial DNA
Authors:Nestor N Oiwa  James A Glazier
Institution:1. Institute of Physics, University of S?o Paulo, S?o Paulo, Brazil
2. Department of Physics, University of Notre Dame, Notre Dame, IN
3. Department of Physics and Biocomplexity Institute, Indiana University, Bloomington, IN
Abstract:We show that repeated sequences, like palindromes (local repetitions) and homologies between two different nucleotide sequences (motifs along the genome), compose a self-similar (fractal) pattern in mitochondrial DNA. This self-similarity comes from the looplike structures distributed along the genome. The looplike structures generate scaling laws in a pseudorandom DNA walk constructed from the sequence, called a Lévy flight. We measure the scaling laws from the generalized fractal dimension and singularity spectrum for mitochondrial DNA walks for 35 different species. In particular, we report characteristic loop distributions for mammal mitochondrial genomes.
Keywords:Fractal  mitochondrial genome  scaling laws  Lévy flight  DNA walk  large-scale DNA analysis  palindromes  DNA loops  16S rRNA
本文献已被 PubMed SpringerLink 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号