Population genetics of the people of Iran II. Genetic differentiation and population structure |
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| Authors: | S. S. Papiha P. Amirshahi E. Sunderland D. D. Farhud S. H. Tavakoli P. Daneshmand |
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| Affiliation: | (1) Division of Human Genetics, School of Pathological Sciences, University of Newcastle upon Tyne, UK;(2) Unit of Human Genetics and Anthropology, School of Public Health, University of Tehran, Iran;(3) University College of North Wales, Bangor, UK |
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| Abstract: | The genetic structure of six populations of Iran (Turks, Kurds, Lurs, Zabolis, Baluchis and Zoroastrians) was examined using data on blood groups, serum proteins and cell enzymes. Our results show conclusively that there are genetic differences among the six populations and the analysis of superimposed R and S matrices defined Harpending & Jenkins (1973) show by that the dispersion of some of the alleles correspond to the dispersion of the populations. The FST estimates are not large enough to favour selection on any of the loci studied. The FIT and FIS estimates are positive and moderately high suggesting that the genetic differentiation to some extent is influenced by inbreeding. |
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| Keywords: | Population genetics Iran population structure |
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