| 阿片肽对大鼠伏核神经元突触后电位的影响 |
| |
| 引用本文： | 袁孝如.阿片肽对大鼠伏核神经元突触后电位的影响[J].生理学报,1993,45(6):528-535. |
| |
| 作者姓名： | 袁孝如 |
| |
| 作者单位： | 南京医学院生理教研室，Department of neuropharmacology，The Scripps Research Institute，La Jolla，CA 92037.U.S.A.，Department of neuropharmacology，The Scripps Research Institute，La Jolla，CA 92037.U.S.A. 南京 210029 |
| |
| 摘 要： | 行为学研究指出，伏核是阿片奖赏作用，和阿片成瘾的关键脑区域，为了在细胞水平上分析阿片作用机理，本文在大鼠伏核脑片制备上，应用细胞内电流箝记录，于不同神经元上分别观察三种阿片肽对膜电位和突触后电位的影响，研究结果表明：所试验的三种阿片肽均不影响神经元的膜电位和输入阻抗，却降低突触后电位；纳洛酮明显地翻转μ和δ受体激动剂的作用，对Ｋａｐｐａ受体激动剂作用翻转不完全。上述结果提示：在伏核内，阿片肽的作用
|
| 关 键 词： | 阿片肽 突触后电位 伏核 神经元 |
THE EFFECTS OF OPIOID PEPTIDES ON POSTSYNAPTIC POTENTIALS IN SLICE PREPARATION OF NUCLEUS ACCUMBENS OF RATS |
| |
| YUAN XIAO-RU,SAMUEL MADAMBA,GEORE ROBERT SIGGINS.THE EFFECTS OF OPIOID PEPTIDES ON POSTSYNAPTIC POTENTIALS IN SLICE PREPARATION OF NUCLEUS ACCUMBENS OF RATS[J].Acta Physiologica Sinica,1993,45(6):528-535. |
| |
| Authors: | YUAN XIAO-RU SAMUEL MADAMBA GEORE ROBERT SIGGINS |
| |
| Institution: | YUAN XIAO-RU,SAMUEL MADAMBA,GEORE ROBERT SIGGINS Department of Physiology,Nanjing Medical College,Nanjing 210029 Department of Neuropharmacology,The Scripps Resarch Institude,La Jolla,CA 92037,U.S.A. |
| |
| Abstract: | |
| |
| Keywords: | brain slice preparation intracellular current-clamp recording opioid peptides opiate re ceptors postsynaptic potentials |
| 本文献已被 CNKI 维普 等数据库收录！ |
