Tyrosine hydroxylase in various brain regions of three strains of mice differing in spontaneous activity, learning ability, and emotionality. |
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Authors: | B Tiplady J J Killian P Mandel |
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Institution: | Centre de Neurochimie du CNRS 11, rue Humann 67085 Strasbourg Cedex - France - |
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Abstract: | Tyrosine hydroxylase has been measured in brains of three inbred strains of mice ; DBA/2J ; C57 BL/6J and BALB/cJ. Compared to C57 BL/6J, DBA/2J showed a higher enzyme activity in hypothalamus, a lower activity in pons-medulla, and no significant changes in cortex or striatum. BALB/cJ showed a higher level of activity in all regions studied (striatum, pons-medulla and hypothalamus). No effect of isolation or of social dominance position were noted on the enzyme activities in C57 BL/6J or BALB/cJ mice. |
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