Finegoldia magna,an early post-operative cause of infectious endocarditis: Report of two cases and review of the literature |
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| Affiliation: | 1. Division of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA;2. Department of Orthopedic Surgery, Mayo Clinic, Rochester, MN 55905, USA;3. Division of Biomedical Statistics and Informatics, Department of Health Science Research, Mayo Clinic, Rochester, MN 55905, USA;4. Division of Infectious Diseases, Department of Medicine, Mayo Clinic, Rochester, MN 55905, USA |
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| Abstract: | We report two cases of infectious endocarditis (IE) on prosthetic valves caused by Finegoldia magna. The diagnosis was obtained by detection of the bacterium in valvular biopsies using 16S rRNA PCR amplication and sequencing, and prolonged culture. Five other cases were previously published in the literature. Following analysis of these seven cases, F. magna endocarditis presented as a subacute endocarditis, developing early (60 days) following valvular replacement (85%), with an elevated mortality (28%). Our report highlights the potential role of F. magna in early post-surgical endocarditis on prosthetic valves. |
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