On the occurrence of macroorchidism and mental handicap in the Aarskog syndrome |
| |
Authors: | J P Fryns H Van den Berghe |
| |
Institution: | Center for Human Genetics, University of Leuven, Belgium. |
| |
Abstract: | In this report we present follow-up on two moderately mentally retarded boys with Aarskog syndrome. As 22 other mentally normal Aarskog patients these two boys presented a catch-up after a delayed puberty with a final adult height of 160 cm. A remarkable finding was the development of macroorchidism in two mentally retarded Aarskog patients. The pathogenesis of macroorchidism in the fragile X syndrome and in other X-linked mental retardation syndromes is discussed. |
| |
Keywords: | |
|