RNA repair: damage control |
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Authors: | Bellacosa Alfonso Moss Eric G |
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Affiliation: | Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111, USA. a_bellacosa@fccc.edu |
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Abstract: | RNA in a cell is subject to many of the same insults as DNA. RNA damage can induce apoptosis and may be exploited for anti-cancer chemotherapy. It is a surprise, however, to learn that cells may repair RNA damage, suggesting a far greater significance of RNA in genotoxic stress. |
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