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Synthesis and antifungal activity of furo[2,3-f]quinolin-5-ols
Authors:Ryu Chung-Kyu  Kim Yang Hui  Nho Ji-Hee  Hong Jung An  Yoon Joo Hee  Kim Aram
Institution:College of Pharmacy, Ewha Womans University, Seodaemun-ku, Seoul 120-750, Republic of Korea
Abstract:Furo2,3-f]quinolin-5-ol derivatives were synthesized and tested for in vitro antifungal activity against Candida,Aspergillus species, and Cryptococcus neoformans. Among them tested, many furo2,3-f]quinolin-5-ols showed good antifungal activity. The results suggest that furo2,3-f]quinolin-5-ols would be promising antifungal agents.
Keywords:Furo[2  3-f]quinolin-5-ols  Antimicrobial compounds  Antifungal  Fungi  Substitution effects
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