Stabilization of microtubules by Combretastatin D derivatives |
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| Authors: | Couladouros E A Li T Moutsos V I Pitsinos E N Soufli I C |
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| Affiliation: | Chemistry Laboratories, Agricultural University of Athens, Greece. ecoula@mail.ariadne-t.gr |
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| Abstract: | The effect of five derivatives of Combretastatin D on tubulin polymerization was investigated. All of them were found to stabilize microtubules to various degrees. The derivatives bearing polar substituents were found to be the most active. |
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