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Structural effects of cofilin on longitudinal contacts in F-actin |
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| Authors: | Bobkov Andrey A Muhlrad Andras Kokabi Kaveh Vorobiev Sergey Almo Steven C Reisler Emil |
| Institution: | Department of Chemistry and Biochemistry and the Molecular Biology Institute, University of California, Los Angeles, CA 90095, USA. abobkov@burnham.org |
| Abstract: | Structural effects of yeast cofilin on skeletal muscle and yeast actin were examined in solution. Cofilin binding to native actin was non-cooperative and saturated at a 1:1 molar ratio, with K(d) |
| Keywords: | actin ADF cofilin DNase I binding loop longitudinal contacts |
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