Microrheological characteristics of reticulocyte in vivo |
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Authors: | XIE Lide SUN Dagong YAO Weijuan& WEN ZongyaoHemorheology Center |
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Institution: | XIE Lide SUN Dagong YAO Weijuan& WEN ZongyaoHemorheology Center,Department of Biophysics,School of Basic Medical Sciences,Peking University,Beijing 100083,China |
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Abstract: | Using the method of phenylhydrazine-induced anemia in rabbits, a mass of new reticu-locytes, which synchronously grow, were got in vivo. The measurements of deformation index, orientation index, electrophoresis mobility etc. were performed for more than 72 h in the process of reticulocytes turning into red blood cells in vivo. There were obvious changes in the micro-rheological characteristics of reticulocytes in the course of turning into erythrocytes. The present study is significant in clinic for studying erythrocytes' microrheological characteristics when there are a lot of reticulocytes in blood, and also important in basic theorem for studying reticulocytes microrheological characteristics. It makes up a deficiency in the study on microrheological characteristics of reticulocytes turning into new RBCs from reticulocytes during reticulocytes life span. |
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Keywords: | phenylhydrazine reticulocyte microrheological characteristics deformation indexes orientation indexes new ektacytometry |
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