首页 | 本学科首页   官方微博 | 高级检索  
     


Highly stereoselective synthesis of C-vinyl furanosides through acid-catalyzed S(N)2 inversion at the C-3 position of 1,2-dideoxy-hept-1-enitols
Authors:Tsuchiya Hitoshi  Asakura Noriaki  Ikeda Yasunori  Yamada Hidetoshi
Affiliation:School of Science and Technology, Kwansei Gakuin University, 2-1 Gakuen, Sanda 669-1337, Japan
Abstract:A highly stereoselective synthesis of C-vinyl furanosides through the SN2 inversion at the C-3 position of the 1,2-dideoxy-hept-1-enitols is disclosed. Treatment of the 1,2-dideoxy-hept-1-enitols with diphenylammonium trifluoromethanesulfonate as the acid catalyst produced the C-vinyl furanosides (3,6-anhydro-1,2-dideoxy-hept-1-enitol derivatives) via a subsequent SN2 intramolecular debenzyloxyation-cycloetherification reaction at the C-3 position.
Keywords:C-Vinyl furanosides   1,2-Dideoxy-hept-1-enitols   SN2 intramolecular debenzyloxyation-cycloetherification   Diphenylammonium trifluoromethanesulfonate
本文献已被 ScienceDirect PubMed 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号